FDA Data · GLP-1/GIP
Mounjaro Reported Side Effects
tirzepatide by Eli Lilly. Approved 2022 for type 2 diabetes.
79,973 total adverse event reports in FAERS
What are the most reported side effects of Mounjaro?
These are the 15 most frequently reported adverse events for Mounjaro in the FDA FAERS database. Higher counts mean more reports, not necessarily higher risk.
Injection Site Pain
8,545
Nausea
8,226
Extra Dose Administered
4,782
Diarrhea
4,775
Vomiting
4,137
Injection Site Haemorrhage
3,319
Constipation
2,901
Injection Site Erythema
2,804
Blood Glucose Increased
2,555
Decreased Appetite
2,042
Fatigue
2,025
Accidental Underdose
1,953
Injection Site Bruising
1,886
Weight Loss
1,754
Upper Abdominal Pain
1,726
Side Effects by Category
Other24 reported side effects
| Injection Site Pain | 8,545 |
| Extra Dose Administered | 4,782 |
| Injection Site Haemorrhage | 3,319 |
| Injection Site Erythema | 2,804 |
| Blood Glucose Increased | 2,555 |
| Accidental Underdose | 1,953 |
| Injection Site Bruising | 1,886 |
| Injection Site Pruritus | 1,467 |
| Illness | 1,453 |
| Accidental Overdose | 1,307 |
| Inappropriate Schedule Of Product Administration | 1,238 |
| Weight Increased | 1,231 |
| Abdominal Discomfort | 1,147 |
| Injection Site Mass | 1,138 |
| Pain | 888 |
| Injection Site Swelling | 883 |
| Gastrointestinal Disorder | 863 |
| Blood Glucose Decreased | 849 |
| Injection Site Reaction | 785 |
| Feeling Abnormal | 780 |
| Injection Site Injury | 780 |
| Injection Site Rash | 779 |
| Product Administered At Inappropriate Site | 726 |
| Hunger | 722 |
Digestive12 reported side effects
| Nausea | 8,226 |
| Diarrhea | 4,775 |
| Vomiting | 4,137 |
| Constipation | 2,901 |
| Upper Abdominal Pain | 1,726 |
| Abdominal Pain | 1,476 |
| Burping (Eructation) | 1,361 |
| Indigestion | 1,185 |
| Delayed Stomach Emptying | 1,108 |
| Pancreatitis | 875 |
| Bloating | 787 |
| Flatulence | 769 |
Metabolic6 reported side effects
| Decreased Appetite | 2,042 |
| Fatigue | 2,025 |
| Weight Loss | 1,754 |
| Dehydration | 1,132 |
| Malaise | 844 |
| Weakness | 778 |
Neurological2 reported side effects
| Headache | 1,633 |
| Dizziness | 1,429 |
Skin & Hair1 reported side effects
| Hair Loss | 849 |
Mental Health1 reported side effects
| Anxiety | 764 |
How does Mounjaro compare to other GLP-1 medications?
Frequently Asked Questions
Important: This data comes from the FDA Adverse Event Reporting System (FAERS), a voluntary reporting system. Report counts do not prove the medication caused the event. Not all adverse events are reported, and reporting rates vary by drug, time since approval, and media attention. This tool is for educational purposes only and is not medical advice. Always consult your healthcare provider about medication side effects.